The U.S. Department of Energy (DOE) has announced new collaboration agreements with 24 organizations to advance the Genesis Mission, a national initiative that aims to use artificial intelligence (AI) for scientific discovery, national security, and energy innovation. This move is in line with President Trump’s Executive Order on removing barriers to American leadership in AI and supports the America’s AI Action Plan introduced earlier this year.
A White House meeting took place today with industry participants, U.S. Secretary of Energy Chris Wright, DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil, and Michael Kratsios, Director of the White House Office of Science and Technology Policy. The meeting marked the launch of public-private partnerships focused on developing scalable national infrastructure for AI-driven science.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
“Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation,” said DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil. “These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The organizations signing memorandums of understanding include technology firms such as Accenture, AMD, Anthropic, Amazon Web Services (AWS), Google, IBM, Intel, Microsoft, NVIDIA, OpenAI; hardware providers like Dell; cloud computing companies such as CoreWeave; research-focused groups like XPRIZE; among others.
These MOUs are part of ongoing efforts by DOE to engage partners from private industry as well as academia in projects related to the Genesis Mission. Products developed under this mission are intended to be architecture-agnostic.
DOE continues to seek additional collaborators through open Requests for Information (RFIs). The “Partnerships for Transformational Artificial Intelligence Models” RFI remains open until January 14th next year while another RFI focused on national security applications is accepting submissions until January 23rd.
More information about the Genesis Mission can be found at www.genesis.energy.gov.

